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Published on:2, 2011
Pharmacognosy Journal, 2011; 3(20):1-4
Original Article | doi:10.5530/pj.2011.20.1

Chemical Examination and Biological Studies on the Bark of Crataeva nurvala Buch.-Ham.

Authors and affiliation (s):

G. Venkateswara Rao*, T. Annamalai, T. Mukhopadhyay

M/s. Cavinkare Research Centre, 12, Poonamalle Road, Ekkattuthangal, Chennai 600 032, India.


In continuation of our investigation on bioactive molecules, the melanin promotion activity-guided fractionation of the methanolic extract of the bark of Crataeva nurvala, yielded two known triterpenoid derivatives, lupeol (1) and lupenone (2). The structure of the compounds were established by physical and spectral data (UV, IR, 1H, 13C NMR and Mass). The compounds were shown potent melanin promotion activity when compared with standard control compound, 3-isobutyl-1-methylxanthine (IBMX).

Key words: Crataeva nurvala, triterpenoids, melanin promotion activity.


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