Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:7:\"warning\";s:8:\"%message\";s:39:\"Invalid argument supplied for foreach()\";s:5:\"%file\";s:81:\"/home/phcogfir/public_html/sites/all/modules/biblio_scholar/biblio_scholar.module\";s:5:\"%line\";i:13;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:62:\"Non-static method view::load() should not be called statically\";s:5:\"%file\";s:63:\"/home/phcogfir/public_html/sites/all/modules/views/views.module\";s:5:\"%line\";i:1118;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:109:\"Declaration of views_handler_field::query() should be compatible with views_handler::query($group_by = false)\";s:5:\"%file\";s:83:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_field.inc\";s:5:\"%line\";i:0;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:136:\"Declaration of views_handler_argument::options_validate() should be compatible with views_handler::options_validate($form, &$form_state)\";s:5:\"%file\";s:86:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_argument.inc\";s:5:\"%line\";i:0;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:112:\"Declaration of views_handler_argument::query() should be compatible with views_handler::query($group_by = false)\";s:5:\"%file\";s:86:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_argument.inc\";s:5:\"%line\";i:0;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:134:\"Declaration of views_handler_filter::options_validate() should be compatible with views_handler::options_validate($form, &$form_state)\";s:5:\"%file\";s:84:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_filter.inc\";s:5:\"%line\";i:0;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:110:\"Declaration of views_handler_filter::query() should be compatible with views_handler::query($group_by = false)\";s:5:\"%file\";s:84:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_filter.inc\";s:5:\"%line\";i:0;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:127:\"Declaration of views_plugin_query::options_submit() should be compatible with views_plugin::options_submit($form, &$form_state)\";s:5:\"%file\";s:81:\"/home/phcogfir/public_html/sites/all/modules/views/plugins/views_plugin_query.inc\";s:5:\"%line\";i:0;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:139:\"Declaration of views_plugin_argument_validate::options_submit() should be compatible with views_plugin::options_submit($form, &$form_state)\";s:5:\"%file\";s:93:\"/home/phcogfir/public_html/sites/all/modules/views/plugins/views_plugin_argument_validate.inc\";s:5:\"%line\";i:0;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:130:\"Declaration of views_plugin_row::options_validate() should be compatible with views_plugin::options_validate(&$form, &$form_state)\";s:5:\"%file\";s:79:\"/home/phcogfir/public_html/sites/all/modules/views/plugins/views_plugin_row.inc\";s:5:\"%line\";i:0;}', 3, '', 'http://phcogfirst.com/article/1079', '', '18.204.2.190', 1618677035) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135
Cytotoxicity and Antioxidant Activity of New Biologically Active Constituents from Salvia Lanigra and Salvia Splendens
Home | Articles
Published on:4, 2011
Pharmacognosy Journal, 2011; 3(21):36-48
Original Article | doi:10.5530/pj.2011.21.7

Cytotoxicity and Antioxidant Activity of New Biologically Active Constituents from Salvia Lanigra and Salvia Splendens


Authors and affiliation (s):

Usama Y. Shaheen1*, Mohammed H. Hussain1 and Hassan A. Ammar2

1 Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.

2 Department of Pharmacognosy, Faculty of Pharmacy, Ahram Canadian University in Egypt, 6th October, Egypt.

Abstract:

Chromatographic fractionation of the acetone extracts of each of Salvia lanigra and Salvia splendens and of the n-butanol extract of Salvia lanigra, resulted in the isolation and identification of two known diterpenes; horminone (1) and 7-O-ethylhorminone (2), three new diterpenes; salviatane B (3), salvianol A (4) and salviaclerodan A (5), two known triterpenioc acids; ursolic acid (6) and oleanolic acid (7), a known sterol; β-sitosterol (8), two known flavones; salvigenin (9) and apigenin (10) and one new caffiec acid dimmer; 3,3’-dehydrodicaffeic acid (11). The cytotoxicity and the antioxidant activity of the different extracts (MeOH, acetone and n-butanol) of both Salvia lanigra and Salvia splendens and most of the isolated pure compounds (1-5, 9 and 10) were determined.

Key words: Salvia, Diterpenes, Phenolics, Cytotoxicity and Antioxidants Activity.

 

Articles in PDF, ePUB and Full text are attached to this page. In order to download, print or access these formats you must be logged in.