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Published on:27th Nov, 2014
Pharmacognosy Journal, 2015; 7(1):01-17
Review Articles | doi:10.5530/pj.2015.1.1

Phytochemicals Having Neuroprotective Properties from Dietary Sources and Medicinal Herbs


Authors and affiliation (s):

G. Phani Kumar*, K.R. Anilakumar and S. Naveen

Applied Nutrition Division, Defence Food Research Laboratory (DRDO), Ministry of Defence, India

Abstract:

Many neuropsychiatric and neurodegenerative disorders, such as Alzheimer's disease, anxiety, cerebrovascular impairment, depression, seizures, Parkinson's disease, etc. are predominantly appearing in the current era due to the stress full lifestyle. Treatment of these disorders with prolonged administration of synthetic drugs will lead to severe side effects. In the recent years, scientists have focused the attention of research towards phytochemicals to cure neurological disorders. Nootropic herb refers to the medicinal role of various plants/parts for their neuroprotective properties by the active phytochemicals including alkaloids, steroids, terpenoids, saponins, phenolics, flavonoids, etc. Phytocompounds from medicinal plants play a major part in maintaining the brain's chemical balance by acting upon the function of receptors for the major inhibitory neurotransmitters. Medicinal plants viz. Valeriana officinalis, Nardostachys jatamansi, Withania somnifera, Bacopa monniera, Ginkgo biloba and Panax ginseng have been used widely in a variety of traditional systems of therapy because of their adaptogenic, psychotropic and neuroprotective properties. This review highlights the importance of phytochemicals on neuroprotective function and other related disorders, in particular their mechanism of action and therapeutic potential.

Key words: Neuroprotection, Phytochemicals, Medicinal herbs, Nootropics, Dietary sources.

 

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