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Pharmacognosy Journal, 2013; 5(3):130-134
Short Communication | doi:10.1016/j.phcgj.2013.04.004

In vitro biological standardization, formulation and evaluation of directly compressed polyherbal anthelmintic tablets


Authors and affiliation (s):

Maddi Ramaiaha,*, Guntupalli Chakravathib, Kanuri Yasaswinia

a Department of Phytochemistry & Pharmacognosy, AU College of Pharmaceutical Sciences, Andhra University, Visakhapatnam 530003, A.P., India

b Department of Pharmacognosy, Mother Teresa Pharmacy College, Khammam 507303, A.P., India

Abstract:

Introduction: Herbal medicines are free from side effects, adverse effects and they are economical and easily available will be beneficial for the mankind over the centuries. Helminth infections are the common infections affecting the large portion of the world’s population and can be easily treated by using medicinal plants. Methods: The present study was aimed to formulate the polyherbal anthelmintic tablets having composition of Uraria lagopoides, Punica granatum, and Saraca asoca by direct compression method using Super Tab 11SD, Primojel, talc and magnesium stearate as excipients and subjected to evaluation of pre compression and post compression parameters. Finally the unit dosage form was evaluated for its anthelmintic activity using Indian adult earthworm Pheretima posthuma. Results and conclusion: Time taken for paralysis, death of the worms was recorded. It was found to be statistically significant.

Key words: Anthelmintic activity,Pre compression parameters,Post compression parameters.

 

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