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Published on:3rd August, 2012
Pharmacognosy Journal, 2012; 4(31):47-53
Original Article | doi:10.5530/pj.2012.31.9

Polyphenolic constituents of the methanolic extract of Callistemon viridiflorous leaves and its antimicrobial activity


Authors and affiliation (s):

Mohamed IS Abdelhady1*, Amel M Kamal1, Nashwa F Tawfik1 and Soad M Abdelkhalik1

1Pharmacognosy Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, Egypt

Abstract:

Introduction: The genus Callistemon (family: Myrtaceae) contains 34 species which are widely distributed in the temperate regions and used in folk medicine. Methods: Chromatographic separation of 80% MeOH extract of the leaves of Callistemon viridiflorus (sims) Sweet (Cv) was performed. Results: Seven known polyphenolic compounds were isolated for the first time from this species: gallic acid, ellagic acid, isoquercetin, hyperin, 1,2:3,4-(bis(s)- hexahydroxy diphenoyl-β-D-glucopyranose, nilocitin and quercetin-3-O-α-L-glucuronopyranoside. The methanolic extract of Cv leaves exhibited a significant anti-microbial activity against the tested microorganisms.

Keywords: Myrtaceae, Callistemon viridiflorous, polyphenols, anti-microbial activity.

 

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