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Published on:20th Dec 2012
Pharmacognosy Journal, 2012; 4(33):23-30
Original Article | doi:10.5530/pj.2012.33.4

Phytochemical screening and antimicrobial activity of ethanol and aqueous extracts of stem of Glyphaea brevis (spreng.) monachino on oral microorganisms

Authors and affiliation (s):

Oshomoh EO and *Idu M

Department of Plant Biology and Biotechnology, Faculty of Life Sciences, University of Benin, Benin city, Edo State. Nigeria


The phytochemistry and antimicrobial activities of the aqueous and ethanolic extracts of the Glyphaea brevis stem was investigated. The results from this study indicate that the antimicrobial activities of the stem of G. brevis are microbe specific. The stem showed a significantly higher antimicrobial activity against Staphylococcus aureus and Streptococcus mutans even at a lower concentration of 3.13 mg/ml. Phytochemical screening of the plant part reveal the presence of alkaloids, flavonoids, anthraqiunones, saponins, steroids, cardiac glycosides, phlobotanins and carbohydrates in both extracts. While tannins and terpenoids were absent in extracts. The potency of the antimicrobial activities of Glyphea brevis plant has made the stem suitable for better dental care and cleansing.

Keywords: Potency, dental care, periodontal disease, medicinal plant.


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