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Published on:12/2010
Pharmacognosy Journal, 2011; 2(18):61-64
Research Article | doi:10.1016/S0975-3575(11)80027-1

Antimicrobial Potential of Eupatorium adenophorum Spreng

Authors and affiliation (s):

Negi Arvind* and Semwal Amit

*Department of Pharmacognosy, GRD (PG) IMT, Rajpur Dehradun Uttarakhand-248001, GISIPS, Department of Pharmacy, Dehra Dun, Uttarakhand-248001.


The antimicrobial activity of Petroleum-ether, Benzene, Chloroform, methanol and aqueous extracts of crude leaves of Eupatorium adenophorum Spreng were tested against the growth of Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, Escherichia coli, Klebsiella aerogenes and Pseudomonas aeruginosa by Paper disk diffusion technique. Nearly all the extracts were found to exhibit moderate to good antibacterial activity against the bacterial pathogens tested and the petroleum ether extract recorded largest zone of inhibition against B.subtilis. The positive results so obtained were compared with that of the reference standard antibiotic ciprofloxacin. Antifungal activity of the above extracts were tested on fungal strains Aspergilus niger, Aspergilus candidus and Candida albicans using Fluconazole as the standard drug. The result shows significant antimicrobial activity of extracts against tested fungi and bacteria.

Key words: Eupatorium adenophorum Spreng, Antibacterial, Antifungal, Extracts.


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