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Published on:11/2010
Pharmacognosy Journal, 2010; 2(16):29-33
Research Article | doi:10.1016/S0975-3575(10)80047-1

Antiproliferative activity of saponin fractions of Chlorophytum borivilianum


Authors and affiliation (s):

S. L. Deore*, S.S. Khadabadi

Govt. College of Pharmacy, Kathora naka, Amravati-444604. (M.S.), INDIA. A B

Abstract:

The purpose of this study was to investigate the anticancer activity of saponin fractions of Chlorophytum borivilianum belonging to family liliaceae. The MTT (methylthiazolyldiphenyl-tetrazolium bromide) and SRB method was used to evaluate the antiproliferative activity of the mehanolic extract and crude saponin extract. DNA fragmentation assay was carried out to confirm antiproliferative activity of selected extract. Findings of the study suggested that the crude saponin extract of C. borivilianum has potential anticancer activity as very good percentage inhibitions are obtained.

Key words: Chlorophytum borivilianum, saponin, antiproliferative, MCF-7

 

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