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Published on:10th sep 2010
Pharmacognosy Journal, 2010; 2(13):554 - 560
Research Article | doi:10.1016/S0975-3575(10)80059-8

Chemical Standardization of Cassia angustifolia Vahl seed


Authors and affiliation (s):

Manjoosha Srivastava, Sharad Srivastava and AKS Rawat

Phytochemistry Division, National Botanical Research Institute, Lucknow-2226 001, (India).

Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute, Lucknow-2226 001, (India).

Abstract:

Cassia angustifolia Vahl, commonly known as ‘Sanaai’, is employed in various indigenous systems of medicine against several diseases. Almost every part of the plant has diverse medicinal properties. The seeds are used as anthelmintic, digestive, to treat piles, skin diseases and abdominal troubles. The present communication deals with the chemical standardization of the seeds of C. angustifolia. The study includes physicochemical studies and development of chemical markers by HPTLC fingerprinting of seed samples from different geographical zones. The study revealed that the seed samples procured from different zones have similar physico-chemical values and chemical profile. However it was noted that the percentage of active principles (sennosides A & B) varied significantly in samples procured from different parts of the country. Detailed chemical studies are useful in establishing physicochemical standards and biologically active chemical markers for correct identification and authentication. Studies also better characterize the plant matrix through componential analysis of active principles for feasible, acceptable, specific and sustainable value added utilization of plant or their individual components. Studies not only explore the possibility of utilization but also co-relates/authenticates the materials with the commercial formulation for market acceptability and competency.

Key words: Cassia angustifolia, HPTLC, Seeds, Sennoside A, Sennoside B.

 

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