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Pharmacognosy Journal, 2009; 1(1):64-66
Research Article | doi:Nill

Phytochemical screening and antimicrobial efficacy of extracts from Averrhoa bilimbi (Oxalidaceace) fruits against human pathogenic bacteria


Authors and affiliation (s):

*Nurul Huda Bt. Abdul Wahab1, Mohd Effendy Bin Abd Wahid2, Mariam Bt. Taib3, Wan
Zuraida Bt.Wan Mohd Zain4 and Sarah Aqilah Bt. Anwar1

1Department of Chemistry, FST, University of Malaysia Terengganu
2 Institute Bioteknologi Marin, Universiti of Malaysia Terengganu
3Department of Biology, FST, University of Malaysia Terengganu
4Chemistry Department, University Teknologi Mara, Kampus Jengka, Pahang

Abstract:

Averrhoa bilimbi fruits have medicinal properties for the effective management of several human ailments. To enhance the pharmacological study for it traditional uses, the fruits were extracted with three different solvent with various polarities which is hexane, chloroform and methanol. All fractions were subjected to the phytochemical screening and antimicrobial activity against gram-positive and gram-negative bacteria using disc-diffusion methods. The preliminary phytochemical screening on the fruits extracts revealed the presence of flavonoids, saponins and triterpenoids but no alkaloids. The chloroform and methanol fruits extract were active on Aeromonas hydrophila, Escherichia coli, Klebsiella pneumoniae, Saccharimyces cerevisiae, Straphylococcus aureus, Streptococcus agalactiae and Bacillus subtilis. The results of our antibacterial study revealed that the fruits extract showed a good inhibitory activity against the tested pathogens compared with the standard antibiotics which is streptomycin. In conclusion, the A. bilimbi fruits posses a potential antibacterial activity that requires through this study.

Keywords: Averrhoa bilimbi, Oxalidaceace, antimicrobial activity, medicinal plants.

 

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