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Pharmacognosy Journal, 2009; 1(3):221-223
Research Article | doi:Nill

Studies of the antifungal and antiviral activity of methanolic extract of leaves of Grewia asiatica.


Authors and affiliation (s):

Kumari Sangita1, Mazumder Avijit2, Pahwa Shilpa*, Jaju Shivkanya1

1 N.I.E.T, Institute of Pharmaceutical Technology, 19, Knowledge Park-II, Greater Noida-201306

2 Dept.of Pharmaceutical Sciences, B.I.T., Mesra, Ranchi.

Abstract:

The plant Grewia asiatica linn. has potential antibacterial activity against a wide range of microorganisms. We have studied the antifungal and antiviral activity of the methanolic extract of leaves of Grewia asiatica. The solvent used for the extraction was Methanol. It was found from the MIC studies that the sensitivity pattern of the organism for the extract was found to be decreased in the order: Candida albicans, Aspergillus thiogenitalis, Penicillium notatum, Penicillium citrinum and Aspergillus niger. So, it was found that it was active maximum against Candida albicans. However, Aspergillus niger was totally resistant against the extract. The examination of antiviral potency of the extract showed the maximum inhibitory property at a concentration of 1000μg/ml against Urdbean leaf crinkle virus.

Key words: Grewia asiatica; Urdbean plant, Urdbean leaf crinkle virus, MIC, Inoculum, Carborandum powder.

 

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