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Review Article | doi:10.5530/ax.2012.2.2.1

Wound healing and antioxidant properties: do they coexist in plants?

Authors and affiliation (s):

Ipek Süntar,1 Esra Küpeli Akkol,1 Lutfun Nahar,2 Satyajit D. Sarker3*

1Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler 06330, Ankara, Turkey

2Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, United Kingdom

3Department of Pharmacy, School of Applied Sciences, University of Wolverhampton, MA Building, Wulfruna Street, Wolverhampton WV1 1LY, United Kingdom.


Introduction: It is known that the wound-healing process can be aided by the presence of antioxidants. Many plants have been reported to possess wound-healing and antioxidant properties. This review aims to appraise published literature and evaluate whether wound-healing and antioxidant properties co-exist in plants. Methods: Web of knowledge, Google Scholar and PubMed were primarily used to search for published reports on wound-healing and antioxidant properties of plants. Other relevant publications, e.g., books and journal articles, were also consulted. Results: Literature search has revealed that several wound-healing plants also possess considerable antioxidant properties as evident from the results of various in vitro and in vivo assays. It has appeared that the wound-healing properties of plants, in most cases, are associated with their antioxidant activities. Conclusions: The wound-healing property and antioxidant activity co-exist in many plant species from a variety of families.

Key words: wound, wound-healing, oxidative stress, antioxidant, plants.


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