Pharmacognosy journal, 2014; 6(3):36-41
Original Article | doi:10.5530/pj.2014.3.6
Chemical Constituents of Dendrobium williamsonii
Abstract:
Objective: Isolation of compounds from Dendrobium williamsonii and evaluation of each isolates for its free radical scavenging, antiherpetic and cytotoxic activities. Results: Six phenolic compounds were isolated including tetratriacontanyltrans- p-coumarate (1), trans-docosanoylferulate (2), 3,3′-dihydroxy-4,5-dimethoxybibenzyl (3), moscatilin (4), apigenin (5) and vanillic acid (6). Among these isolates, compounds 3, 4 and 5 exhibited recognizable DPPH free radical scavenging potential.Only 3 exhibited weak activity against Herpes simplex virus, whereas 3 and 4 showed cytotoxicity against KB and MCF-7 cancer cells. Conclusion: This study is the first report on the chemical and biological properties of D. williamsonii.Compounds 3, 4 and 5 are responsible for free radical scavenging activity of this plant. Compound 4 showed the strongest cytotoxic effect on KB cancer cells.
Key words: Dendrobium williamsonii, Orchidaceae, Anti-herpetic Cytotoxicity, Free radical scavenging activity.
Articles in PDF, ePUB and Full text are attached to this page. In order to download, print or access these formats you must be logged in.
-
Vancouver Style:
AMA Style:
"Chemical Constituents of Dendrobium williamsonii." Pharmacognosy journal. 2014;6(3):36-41. Abstract
CSE Style:
.
2014. Chemical Constituents of Dendrobium williamsonii. Pharmacognosy journal. 6(3):36-41. Abstract
- Anti-Nociceptive Synergism of Pregabalin and Xylopic acid Co-administration in Paclitaxel-induced Neuropathy: Isobolographic Analysis
- In vivo Antimalarial Evaluation of Embelin and its Semi-Synthetic Aromatic Amine Derivatives
- Upcoming Events
- In vitro effect of Citrullus colocynthis and Acacia raddiana on Phosphate Calcium Crystallization