Pharmacognosy Journal, 2014; 6(1):43-46
Original Article | doi:10.5530/pj.2014.1.7
15-Lipoxygenase inhibition of selected Philippine medicinal plants
Several extracts from Philippine medicinal plants used for asthma and other inflammatory diseases were evaluated for their ability to inhibit the action of 15-lipoxygenase. The inhibitory activity was tested spectrophotometrically using quercetin as positive control. Eleven species belonging to 11 families displayed varying inhibitory activities. Commelina diffusa and Euphorbia hirta showed the highest inhibitory activity at 51.3% and 48.5%, respectively. These plants may contain new 15-lipoxygenase inhibitors.
Key words: Asthma, inflammation, lipoxygenase, medicinal plants, plant extra.
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