Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:62:\"Non-static method view::load() should not be called statically\";s:5:\"%file\";s:63:\"/home/phcogfir/public_html/sites/all/modules/views/views.module\";s:5:\"%line\";i:1118;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:109:\"Declaration of views_handler_field::query() should be compatible with views_handler::query($group_by = false)\";s:5:\"%file\";s:83:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_field.inc\";s:5:\"%line\";i:0;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:136:\"Declaration of views_handler_argument::options_validate() should be compatible with views_handler::options_validate($form, &$form_state)\";s:5:\"%file\";s:86:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_argument.inc\";s:5:\"%line\";i:0;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:112:\"Declaration of views_handler_argument::query() should be compatible with views_handler::query($group_by = false)\";s:5:\"%file\";s:86:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_argument.inc\";s:5:\"%line\";i:0;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:134:\"Declaration of views_handler_filter::options_validate() should be compatible with views_handler::options_validate($form, &$form_state)\";s:5:\"%file\";s:84:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_filter.inc\";s:5:\"%line\";i:0;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:110:\"Declaration of views_handler_filter::query() should be compatible with views_handler::query($group_by = false)\";s:5:\"%file\";s:84:\"/home/phcogfir/public_html/sites/all/modules/views/handlers/views_handler_filter.inc\";s:5:\"%line\";i:0;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:127:\"Declaration of views_plugin_query::options_submit() should be compatible with views_plugin::options_submit($form, &$form_state)\";s:5:\"%file\";s:81:\"/home/phcogfir/public_html/sites/all/modules/views/plugins/views_plugin_query.inc\";s:5:\"%line\";i:0;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:139:\"Declaration of views_plugin_argument_validate::options_submit() should be compatible with views_plugin::options_submit($form, &$form_state)\";s:5:\"%file\";s:93:\"/home/phcogfir/public_html/sites/all/modules/views/plugins/views_plugin_argument_validate.inc\";s:5:\"%line\";i:0;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135

Warning: Table './phcogfir_phcogfs/dr_watchdog' is marked as crashed and should be repaired query: INSERT INTO dr_watchdog (uid, type, message, variables, severity, link, location, referer, hostname, timestamp) VALUES (0, 'php', '%message in %file on line %line.', 'a:4:{s:6:\"%error\";s:14:\"strict warning\";s:8:\"%message\";s:130:\"Declaration of views_plugin_row::options_validate() should be compatible with views_plugin::options_validate(&$form, &$form_state)\";s:5:\"%file\";s:79:\"/home/phcogfir/public_html/sites/all/modules/views/plugins/views_plugin_row.inc\";s:5:\"%line\";i:0;}', 3, '', 'https://phcogfirst.com/article/142', '', '3.236.50.201', 1627860816) in /home/phcogfir/public_html/includes/database.mysql.inc on line 135
Antiepileptic activities of the extract and fractions of Mondia whitei (Hook f.) Skeel leaves
Home | Articles
Published on:
Pharmacognosy Journal, 2013; 5(6):256-258
Original Article | doi:10.1016/j.phcgj.2013.10.004

Antiepileptic activities of the extract and fractions of Mondia whitei (Hook f.) Skeel leaves


Authors and affiliation (s):

Adediwura A. Fred-Jaiyesimi*, Oluwatosin F. Ogunjobi

Department of Pharmacognosy, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu Campus, Ogun State, Nigeria

Abstract:

Objectives: To investigate the antiepileptic potentials of Mondia whitei (Hook f.) Skeel leaves as identified in the folklore recipes for the management of paralysis, epilepsy. M. whitei is also used in antimalarial, antihelminthic recipes as well as in the treatment of impotence and sexual dysfunction. Methodology: The antiepileptic study of the methanol extract, hexane and ethyl acetate fractions were carried out using the pilocarpine induced seizure model while the Phytochemical and fluorescence analysis were carried out using standard procedures. Result: The presence of saponins, flavonoids, tannins and resins were detected in the leaves of M. whitei. The extract and fractions exhibited a dose-dependent effect in the delay of the onset of seizures and reduction in the duration of seizure. Conclusion: This study justifies the use of M. whitei in folklore medicine as a recipe in the management of epilepsy.

Key words: Mondia whitei, Epilepsy, Pilocarpine, Phytochemical and fluorescence analysis.

 

Articles in PDF, ePUB and Full text are attached to this page. In order to download, print or access these formats you must be logged in.




 

Article Links