Pharmacognosy Journal, 2013; 5(6):265-268
Original Article | doi:10.1016/j.phcgj.2013.09.005
Phytochemical and GC-MS analysis of bioactive compounds of Sphaeranthus amaranthoides Burm
Objective: To isolate and analyze the phytochemical constituents of Sphaeranthus amaranthoides using GCeMS. Method: Preliminary phytochemical screening of the extract was carried out according to the standard method described by Brindha et al. GCeMS analysis was performed on the methanolic extract of S. amaranthoides to find out the chemical constituents. Results: Phytochemical screening revealed the presence of steroids, alkaloids, sugars, phenolics, flavonoids, saponins, tannins and amino acids with mottled degree. GCeMS results revealed the presence of 23 different phytocompounds viz., 2-Propenoic acid, 2-methyl-, 2-[[2,3,3a,4,7,7a(or 3a,4,5,6,7,7a)-hexahydro- 4,7-methano-1H-indenyl]oxy] ethyl ester (32.73%), Methanone, (1-hydroxycyclohexyl)phenyl - (13.71%), Methyl 2-bromomethyl-10-tetrahydropyranyloxy-2-decenoate - (7.84%),4,7-Methano-1Hindene, 3a,4,5,6,7,7a-hexahydro-5-(2-propenyloxy) - (6.27%), Primidone - (4.50%), 2-Propenoic acid, 1,7,7-trimethylbicyclo[2.2.1]hept-2-yl ester, exo -(3.78%) and normorphine, bis(o-trimethylsilyl) -(3.65%) etc. Conclusion: The presence of various bioactive compounds confirms the application of S. amaranthoides for various diseases by traditional practitioners. However, isolation of individual phytochemical constituents may proceed to find a novel drug.
Key words: Asteraceae, GCeMS study, Methanol extract, Soxhlet extractor.
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